pentobarbital will reduce the extent or effect of pimozide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.
Contraindicated (1)pentobarbital will lower the extent or effect of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Monitor Carefully (one)pentobarbital will minimize the level or impact of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or impact of bosentan by influencing hepatic enzyme CYP2C9/ten metabolism. Slight/Importance Unknown.
pentobarbital will reduce the extent or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Barbiturates could cause fetal injury when administered to some pregnant woman; retrospective, situation-controlled scientific studies have advised a link involving maternal intake of barbiturates and an increased-than-expected incidence of fetal abnormalities
pentobarbital will decrease the level or impact of isavuconazonium sulfate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will reduce the extent or impact of parecoxib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
fentanyl transdermal and pentobarbital both increase sedation. Steer clear of or Use Alternate Drug. Restrict use to people for whom substitute therapy solutions are read more insufficient
pentobarbital will lessen the extent or result of aprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Monitor Carefully (one)pentobarbital will boost the amount or impact of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or influence of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Effect of coadministering a powerful CYP3A4 inducer with fedratinib has not been studied.
With therapeutic doses of TCAs, barbiturates maximize metabolism and reduce blood concentrations of TCAs.
buprenorphine transdermal and pentobarbital each raise sedation. Prevent or Use Alternate Drug. Limit use to patients for whom different procedure selections are inadequate